Mouse Nr2e3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nr2e3
Locus ID	23958
Kit Components	GA204832G1, Nr2e3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204832G2, Nr2e3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204832G3, Nr2e3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_013708
Synonyms	A930035N01Rik; PNR; rd7; RNR
Summary	Orphan nuclear receptor of retinal photoreceptor cells. Transcriptional factor that is an activator of rod development and repressor of cone development. Binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. Enhances rhodopsin expression. Represses M- and S-cone opsin expression.[UniProtKB/Swiss-Prot Function]

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