Mouse Map2k5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Map2k5
Locus ID	23938
Kit Components	GA204822G1, Map2k5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204822G2, Map2k5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204822G3, Map2k5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011840, NM_001364492, NM_001364493, NM_001364494
Synonyms	AI324775; AI428457; Mapkk5; MEK5; Prkmk5
Summary	Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis.[UniProtKB/Swiss-Prot Function]

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