Mouse Ikzf3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ikzf3
Locus ID	22780
Kit Components	GA204744G1, Ikzf3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204744G2, Ikzf3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204744G3, Ikzf3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_011771
Synonyms	5830411O07Rik; Aiolos; Zfpn1a3; Znfn1a3
Summary	Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Binds to GGGAA. Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2-dependent manner.[UniProtKB/Swiss-Prot Function]

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