Mouse Wnt10b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Wnt10b
Locus ID	22410
Kit Components	GA204633G1, Wnt10b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204633G2, Wnt10b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204633G3, Wnt10b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011718
Synonyms	Wnt12
Summary	Member of the Wnt ligand gene family that encodes for secreted proteins, which activate the Wnt signaling cascade. Specifically activates canonical Wnt/beta-catenin signaling and thus triggers beta-catenin/LEF/TCF-mediated transcriptional programs. Involved in signaling networks controlling stemness, pluripotency and cell fate decisions. Acts in the immune system, mammary gland, adipose tissue, bone and skin.[UniProtKB/Swiss-Prot Function]

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