Mouse Vwf activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Vwf
Locus ID	22371
Kit Components	GA204614G1, Vwf gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204614G2, Vwf gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204614G3, Vwf gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011708
Synonyms	6820430P06Rik; AI551257; B130011O06Rik; C630030D09; F8VWF; VWD
Summary	Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.[UniProtKB/Swiss-Prot Function]

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