Mouse Ube2m activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ube2m
Locus ID	22192
Kit Components	GA204515G1, Ube2m gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204515G2, Ube2m gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204515G3, Ube2m gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001168469, NM_001243968, NM_145578
Synonyms	2510040H03Rik; Ubc-rs2; UBC12
Summary	Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. Involved in cell proliferation (By similarity).[UniProtKB/Swiss-Prot Function]

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