Mouse Tyrp1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tyrp1
Locus ID	22178
Kit Components	GA204508G1, Tyrp1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204508G2, Tyrp1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204508G3, Tyrp1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001282014, NM_001282015, NM_031202
Synonyms	b; brown; isa; Oca3; TRP-1; TRP1; Tyrp
Summary	Plays a role in melanin biosynthesis (PubMed:2245916). Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid (PubMed:7813420). May regulate or influence the type of melanin synthesized (PubMed:7813420, PubMed:2245916). Also to a lower extent, capable of hydroxylating tyrosine and producing melanin (PubMed:1537333).[UniProtKB/Swiss-Prot Function]

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