Mouse Dedd activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dedd
Locus ID	21945
Kit Components	GA204400G1, Dedd gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204400G2, Dedd gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204400G3, Dedd gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001128609, NM_011615, NM_001357550, NM_001357551, NM_001357552, NM_001357553
Synonyms	CASP8IP1; Dedpro1; DEFT; FLDED1; KE05
Summary	A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3 (By similarity). Inhibits DNA transcription in vitro.[UniProtKB/Swiss-Prot Function]

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