Mouse Tfcp2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tfcp2
Locus ID	21422
Kit Components	GA204247G1, Tfcp2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204247G2, Tfcp2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204247G3, Tfcp2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001289603, NM_033476, NM_001355497
Synonyms	CP-2; CP2; D230015P20Rik; LBP-1c; LBP-1d; LBP1; LSF; Tcfcp2; UBP-1
Summary	Binds a variety of cellular promoters including fibrinogen, alpha-globin promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1 (By similarity). Functions as part of the SSP (stage selector protein) complex. Facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. Interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter (By similarity).[UniProtKB/Swiss-Prot Function]

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