Mouse Scarb1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Scarb1
Locus ID	20778
Kit Components	GA204101G1, Scarb1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204101G2, Scarb1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204101G3, Scarb1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001205082, NM_001205083, NM_016741
Synonyms	AI120173; CD36; Cd36l1; Chohd1; Cla-1; Cla1; D5Ertd460e; Hdlq1; Hlb398; mSR-BI; SR-B1; SR-BI
Summary	Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells (By similarity). Both isoform 1 and isoform 2 act as receptors for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux (PubMed:9254074, PubMed:9614139). Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity (By similarity).[UniProtKB/Swiss-Prot Function]

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