Mouse Snap25 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Snap25
Locus ID	20614
Kit Components	GA203999G1, Snap25 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203999G2, Snap25 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203999G3, Snap25 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001291056, NM_011428, NM_001355254, NM_001355255, NR_149318
Synonyms	Bdr; GENA70; SNAP-25; sp; SUP
Summary	t-SNARE involved in the molecular regulation of neurotransmitter release (PubMed:8243676, PubMed:8103915). May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF (PubMed:16672379). Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells (By similarity).[UniProtKB/Swiss-Prot Function]

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