Mouse Slc1a3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Slc1a3
Locus ID	20512
Kit Components	GA203941G1, Slc1a3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203941G2, Slc1a3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203941G3, Slc1a3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_148938
Synonyms	AI504299; B430115D02Rik; Eaat1; GLAST; GLAST-1; GLU-T; GluT-1; Gmt1; MGluT1
Summary	Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:7903437, PubMed:28032905). Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion (By similarity). Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (PubMed:15363892, PubMed:15390100,PubMed:16880397).[UniProtKB/Swiss-Prot Function]

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