Mouse Rit1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rit1
Locus ID	19769
Kit Components	GA203643G1, Rit1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203643G2, Rit1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203643G3, Rit1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001163310, NM_009069, NR_028056
Synonyms	RIBB; Rit; ROC1
Summary	Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation, survival, and differentiation (By similarity).[UniProtKB/Swiss-Prot Function]

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