Mouse Rfxank activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rfxank
Locus ID	19727
Kit Components	GA203628G1, Rfxank gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203628G2, Rfxank gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203628G3, Rfxank gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001025589, NM_011266
Synonyms	Tvl1
Summary	Activates transcription from class II MHC promoters. Activation requires the activity of the MHC class II transactivator/CIITA. May regulate other genes in the cell. RFX binds the X1 box of MHC-II promoters (By similarity). May also potentiate the activation of RAF1 (PubMed:10329666).[UniProtKB/Swiss-Prot Function]

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