Mouse Rdh5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rdh5
Locus ID	19682
Kit Components	GA203599G1, Rdh5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203599G2, Rdh5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203599G3, Rdh5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_134006, NM_001358527
Synonyms	9-cis; AI987873; cRDH; RDH4
Summary	Catalyzes the oxidation of cis-isomers of retinol, including 11-cis-, 9-cis-, and 13-cis-retinol in an NAD-dependent manner (PubMed:10588954, PubMed:9539749). Has no activity towards all-trans retinal (By similarity). Plays a significant role in 11-cis retinol oxidation in the retinal pigment epithelium cells (RPE). Also recognizes steroids (androsterone, androstanediol) as its substrates (By similarity).[UniProtKB/Swiss-Prot Function]

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