Mouse Ptpre activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ptpre
Locus ID	19267
Kit Components	GA203489G1, Ptpre gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203489G2, Ptpre gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203489G3, Ptpre gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001316678, NM_001316679, NM_001316680, NM_001316681, NM_011212
Synonyms	PTPe; PTPepsilon; RPTPepsilon
Summary	Isoform 1 acts as a negative regulator of insulin receptor (IR) signaling and is involved in insulin-induced glucose metabolism mainly through direct dephosphorylation and inactivation of IR in hepatocytes and liver (By similarity). Plays a critical role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function.[UniProtKB/Swiss-Prot Function]

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