Mouse Ptcra activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ptcra
Locus ID	19208
Kit Components	GA203444G1, Ptcra gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203444G2, Ptcra gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203444G3, Ptcra gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_011195
Synonyms	gp33; pT-alpha; pT-alpha-TCR; pTa; pTalpha; pT[a]
Summary	The pre-T-cell receptor complex (composed of PTCRA, TCRB and the CD3 complex) regulates early T-cell development. Isoform 1 acts to retain most TCRB intracellularly, while isoform 2 permits higher levels of cell surface TCRB expression and facilitates signaling from the CD3-TCRB complex.[UniProtKB/Swiss-Prot Function]

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