Mouse St14 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	St14
Locus ID	19143
Kit Components	GA203413G1, St14 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203413G2, St14 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203413G3, St14 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_011176
Synonyms	Epithin; matriptase; mCAP3; MT-SP1; Prss14; Tmprss14
Summary	Degrades extracellular matrix. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site (By similarity). Involved in the terminal differentiation of keratinocytes through prostasin (PRSS8) activation and filaggrin (FLG) processing (By similarity).[UniProtKB/Swiss-Prot Function]

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