Mouse Ppm1b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ppm1b
Locus ID	19043
Kit Components	GA203352G1, Ppm1b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203352G2, Ppm1b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203352G3, Ppm1b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001159496, NM_001159497, NM_001159498, NM_011151
Synonyms	PP2CB
Summary	Enzyme with a broad specificity. Dephosphorylates PRKAA1 and PRKAA2. Inhibits TBK1-mediated antiviral signaling by dephosphorylating it at 'Ser-172'. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.[UniProtKB/Swiss-Prot Function]

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