Mouse Papola activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Papola
Locus ID	18789
Kit Components	GA203272G1, Papola gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203272G2, Papola gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203272G3, Papola gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001347440, NM_011112
Synonyms	Pap; PapIII; Plap
Summary	Polymerase that creates the 3'-poly(A) tail of mRNA's. Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites. May acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus.[UniProtKB/Swiss-Prot Function]

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