Mouse Pitx2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pitx2
Locus ID	18741
Kit Components	GA203235G1, Pitx2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203235G2, Pitx2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203235G3, Pitx2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001042502, NM_001042504, NM_001286942, NM_001287048, NM_011098
Synonyms	9430085M16Rik; Brx1; Brx1b; Munc30; Otlx2; Ptx2; Rieg
Summary	Controls cell proliferation in a tissue-specific manner and is involved in morphogenesis. During embryonic development, exerts a role in the expansion of muscle progenitors. May play a role in the proper localization of asymmetric organs such as the heart and stomach. Isoform Ptx2c is involved in left-right asymmetry the developing embryo.[UniProtKB/Swiss-Prot Function]

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