Mouse Pemt activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pemt
Locus ID	18618
Kit Components	GA203173G1, Pemt gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203173G2, Pemt gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203173G3, Pemt gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001290011, NM_001290012, NM_001290013, NM_001290014, NM_008819
Synonyms	PEAMT; Pempt; Pempt2; PEMT2; PLMT
Summary	Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC).[UniProtKB/Swiss-Prot Function]

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