Mouse Pcbp2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pcbp2
Locus ID	18521
Kit Components	GA203113G1, Pcbp2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203113G2, Pcbp2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203113G3, Pcbp2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001103165, NM_001103166, NM_001174073, NM_011042
Synonyms	alphaCP-2; AW412548; Hnrpx
Summary	Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling. It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitinationa and degradation (By similarity).[UniProtKB/Swiss-Prot Function]

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