Mouse P2rx7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	P2rx7
Locus ID	18439
Kit Components	GA203078G1, P2rx7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203078G2, P2rx7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203078G3, P2rx7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001038839, NM_001038845, NM_001038887, NM_001284402, NM_011027
Synonyms	AI467586; P2X(7); P2X7R
Summary	Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells. In the absence of its natural ligand, ATP, functions as a scavenger receptor in the recognition and engulfment of apoptotic cells.[UniProtKB/Swiss-Prot Function]

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