Mouse Nkx2-2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nkx2-2
Locus ID	18088
Kit Components	GA202908G1, Nkx2-2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202908G2, Nkx2-2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202908G3, Nkx2-2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001077632, NM_010919
Synonyms	Nkx-2.2; Nkx2.2; tinman
Summary	Transcriptional activator involved in the development of insulin-producting beta cells in the endocrine pancreas (PubMed:11076772). May also be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Binds to elements within the NEUROD1 promoter (PubMed:19759004).[UniProtKB/Swiss-Prot Function]

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