Mouse Nfix activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nfix
Locus ID	18032
Kit Components	GA202882G1, Nfix gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202882G2, Nfix gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202882G3, Nfix gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001081981, NM_001081982, NM_001297601, NM_010906
Synonyms	CTF; NF-I/X; NF1-X; NFI-X
Summary	Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. Isoform NFIX1 acts as a transcriptional activator while isoform NFIX3 acts as a repressor.[UniProtKB/Swiss-Prot Function]

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