Mouse Nes activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nes
Locus ID	18008
Kit Components	GA202862G1, Nes gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202862G2, Nes gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202862G3, Nes gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_016701
Synonyms	AA166324; C78523; ESTM46; Ifaprc2; Marc2; RC2
Summary	Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division (By similarity). Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.[UniProtKB/Swiss-Prot Function]

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