Mouse Meis2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Meis2
Locus ID	17536
Kit Components	GA202714G1, Meis2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202714G2, Meis2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202714G3, Meis2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001136072, NM_001159567, NM_001159568, NM_001159569, NM_001159570, NM_010825
Synonyms	A430109D20Rik; Mrg1; Stra10
Summary	This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcriptional regulators and several members have been shown to be essential contributors to developmental programs. In mice, a knock-out of this gene leads to lethality at embryonic day 14, accompanied with hemorrhaging. Embryos lacking this gene show defects in tissues derived from the neural crest, suggesting a critical role of this gene during cranial and cardiac neural crest cell development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]

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