Mouse Mmp3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mmp3
Locus ID	17392
Kit Components	GA202683G1, Mmp3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202683G2, Mmp3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202683G3, Mmp3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_010809
Synonyms	EMS-2; MMP-3; SL-1; SLN-1; SLN1; Stmy1; STR-1; Str1
Summary	This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded protein is activated by the removal of an N-temrinal activation peptide to generate a zinc-dependent endopeptidase with a broad range of substrates such as proteoglycans, laminin, fibronectin, elastin, and collagens. This gene is located in a cluster of other matrix metalloproteinase genes on chromosome 9. [provided by RefSeq, Feb 2016]

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