Mouse Mllt10 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mllt10
Locus ID	17354
Kit Components	GA202668G1, Mllt10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202668G2, Mllt10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202668G3, Mllt10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001252560, NM_001252561, NM_010804, NR_045538, NR_045539, NR_149308
Synonyms	Af10; B130021D15Rik; D630001B22Rik; mKIAA4140
Summary	Probably involved in transcriptional regulation. Binds to cruciform DNA (By similarity). In cells, binding to unmodified histone H3 regulates DOT1L functions including histone H3 'Lys-79' dimethylation (H3K79me2) and gene activation (By similarity).[UniProtKB/Swiss-Prot Function]

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