Mouse Ly6e activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ly6e
Locus ID	17069
Kit Components	GA202521G1, Ly6e gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202521G2, Ly6e gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202521G3, Ly6e gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001164036, NM_001164037, NM_001164038, NM_001164039, NM_001164040, NM_008529
Synonyms	Ly67; RIG-E; Sca-2; TSA-1; Tsa1
Summary	Involved in T-cell development (PubMed:8258699). Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4-containing nAChRs maximum response (PubMed:26276394).[UniProtKB/Swiss-Prot Function]

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