Mouse Lasp1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Lasp1
Locus ID	16796
Kit Components	GA202417G1, Lasp1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202417G2, Lasp1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202417G3, Lasp1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_010688
Synonyms	AA408629; Def-4; SH3P6; Tg(Col1a1-lacZ)1Ngma
Summary	Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity).[UniProtKB/Swiss-Prot Function]

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