Mouse Khsrp activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Khsrp
Locus ID	16549
Kit Components	GA202293G1, Khsrp gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202293G2, Khsrp gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202293G3, Khsrp gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_010613
Synonyms	6330409F21Rik; Fbp2; Fubp2; Ksrp
Summary	Binds to the dendritic targeting element and may play a role in mRNA trafficking. Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3' UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs (By similarity).[UniProtKB/Swiss-Prot Function]

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