Mouse Itm2b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Itm2b
Locus ID	16432
Kit Components	GA202220G1, Itm2b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202220G2, Itm2b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202220G3, Itm2b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_008410
Synonyms	AI256040; Bri; Bri2; Bricd2b; D14Sel6; E25BMM; imBRI2
Summary	Plays a regulatory role in the processing of the amyloid-beta A4 precursor protein (APP) and acts as an inhibitor of the amyloid-beta peptide aggregation and fibrils deposition. Plays a role in the induction of neurite outgrowth. Functions as a protease inhibitor by blocking access of secretases to APP cleavage sites (By similarity).[UniProtKB/Swiss-Prot Function]

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