Mouse Il18r1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Il18r1
Locus ID	16182
Kit Components	GA202139G1, Il18r1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202139G2, Il18r1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202139G3, Il18r1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001161842, NM_001161843, NM_008365
Synonyms	Il1rrp; Il18ralpha
Summary	Within the IL18 receptor complex, responsible for the binding of the proinflammatory cytokine IL18, but not IL1A nor IL1B. Involved in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (By similarity). Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3 (PubMed:26099046).[UniProtKB/Swiss-Prot Function]

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