Mouse Grid2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Grid2
Locus ID	14804
Kit Components	GA201735G1, Grid2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201735G2, Grid2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201735G3, Grid2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_008167
Synonyms	B230104L07Rik; cpr; GluD2; GluRdelta2; ho; Lc; Lc; MMS10-AC; Ms10ac; nmf408; tpr
Summary	Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. Promotes synaptogenesis and mediates the D-Serine-dependent long term depression signals and AMPA receptor endocytosis of cerebellar parallel fiber-Purkinje cell (PF-PC) synapses through the beta-NRX1-CBLN1-GRID2 triad complex.[UniProtKB/Swiss-Prot Function]

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