Mouse Gli1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Gli1
Locus ID	14632
Kit Components	GA201628G1, Gli1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201628G2, Gli1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201628G3, Gli1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_010296
Synonyms	AV235269; Zfp-5; Zfp5
Summary	Acts as a transcriptional activator. Binds to the DNA consensus sequence 5'-GACCACCCA-3'. Regulates the transcription of specific genes during normal development. Plays a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling. Plays a role in cell proliferation and differentiation via its role in SHH signaling.[UniProtKB/Swiss-Prot Function]

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