Mouse Timm10b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Timm10b
Locus ID	14356
Kit Components	GA201490G1, Timm10b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201490G2, Timm10b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201490G3, Timm10b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_019502, NM_001360052, NM_001360053, NM_001360054, NM_001360055, NM_001360056, NM_001360058, NM_001360059, NM_001360060, NM_001360061, NR_153392, NR_153393
Synonyms	Fxc1; Tim9b; Tim10b
Summary	Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as the external driving force. In the TIM22 complex, it may act as a docking point for the soluble 70 kDa complex that guides the target proteins in transit through the aqueous mitochondrial intermembrane space.[UniProtKB/Swiss-Prot Function]

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