Mouse Fgfr3 activation kit by CRISPRa
CAT#: GA201411
Fgfr3 CRISPRa kit - CRISPR gene activation of mouse fibroblast growth factor receptor 3
CN¥ 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Fgfr3 |
Locus ID | 14184 |
Kit Components | GA201411G1, Fgfr3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201411G2, Fgfr3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201411G3, Fgfr3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_001163215, NM_001163216, NM_001163217, NM_001205270, NM_008010 |
Synonyms | CD333; Fgfr-3; Flg-2; FR3; HBGFR; Mfr3; sam3 |
Summary | This gene encodes a member of the fibroblast growth factor receptor family. Members of this family are highly conserved proteins that differ from one another in their ligand affinities and tissue distribution. A representative protein consists of an extracellular region composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene may be associated with craniosynostosis and multiple types of skeletal dysplasia. A pseudogene of this gene is located on chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2011] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN505948 | Fgfr3 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CN¥ 8,680.00 |