Mouse Enah activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Enah
Locus ID	13800
Kit Components	GA201240G1, Enah gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201240G2, Enah gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201240G3, Enah gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001083120, NM_001083121, NM_008680, NM_010135
Synonyms	Mena; NDPP-1; Ndpp1; WBP8
Summary	Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. ENAH induces the formation of F-actin rich outgrowths in fibroblasts. Acts synergistically with BAIAP2-alpha and downstream of NTN1 to promote filipodia formation.[UniProtKB/Swiss-Prot Function]

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