Mouse Eif4a1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Eif4a1
Locus ID	13681
Kit Components	GA201214G1, Eif4a1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201214G2, Eif4a1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201214G3, Eif4a1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001159375, NM_144958
Synonyms	BM-010; Ddx2a; Eif4
Summary	ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.[UniProtKB/Swiss-Prot Function]

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