Mouse Dvl2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dvl2
Locus ID	13543
Kit Components	GA201154G1, Dvl2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201154G2, Dvl2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201154G3, Dvl2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_007888
Summary	Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Participates both in canonical and non-canonical Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling.[UniProtKB/Swiss-Prot Function]

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