Mouse Dnm2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dnm2
Locus ID	13430
Kit Components	GA201106G1, Dnm2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201106G2, Dnm2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201106G3, Dnm2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001039520, NM_001253893, NM_001253894, NM_007871, NM_001357719, NM_001357718, NM_001357721
Synonyms	b2b2159Clo; Dyn2; Udnm
Summary	Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis (PubMed:18923138). Regulates maturation of apoptotic cell corpse-containing phagosomes by recruiting PIK3C3 to the phagosome membrane (PubMed:18425118).[UniProtKB/Swiss-Prot Function]

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