Mouse Dync1i2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dync1i2
Locus ID	13427
Kit Components	GA201104G1, Dync1i2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201104G2, Dync1i2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201104G3, Dync1i2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001198872, NM_001198873, NM_001198874, NM_001198875, NM_001198876, NM_001198877, NM_001198878, NM_001347173, NM_010064
Synonyms	3110079H08Rik; AW554389; Dncic2
Summary	Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. Involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes (By similarity).[UniProtKB/Swiss-Prot Function]

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