Mouse Cyp8b1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cyp8b1
Locus ID	13124
Kit Components	GA201005G1, Cyp8b1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201005G2, Cyp8b1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201005G3, Cyp8b1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_010012
Summary	Involved in bile acid synthesis and is responsible for the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7 alpha, 12 alpha-dihydroxy-4-cholesten-3-one. Responsible for the balance between formation of cholic acid and chenodeoxycholic acid. Has a rather broad substrate specificity including a number of 7-alpha-hydroxylated C27 steroids.[UniProtKB/Swiss-Prot Function]

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