Mouse Runx1t1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Runx1t1
Locus ID	12395
Kit Components	GA200555G1, Runx1t1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200555G2, Runx1t1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200555G3, Runx1t1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001111026, NM_001111027, NM_009822
Synonyms	Cbfa2t1h; ETO; MTG8
Summary	Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes. Can repress the expression of MMP7 in a ZBTB33-dependent manner. Can repress transactivation mediated by TCF12 (By similarity). Acts as a negative regulator of adipogenesis (PubMed:23527555).[UniProtKB/Swiss-Prot Function]

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