Mouse Cask activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cask
Locus ID	12361
Kit Components	GA200532G1, Cask gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200532G2, Cask gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200532G3, Cask gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001284503, NM_001284504, NM_001284505, NM_009806
Synonyms	DXPri1; DXRib1; LIN-2; mLin-2; Pals3
Summary	Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins, and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1.[UniProtKB/Swiss-Prot Function]

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