Mouse Nr1i3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nr1i3
Locus ID	12355
Kit Components	GA200530G1, Nr1i3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200530G2, Nr1i3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200530G3, Nr1i3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001243062, NM_001243063, NM_009803
Synonyms	AA209988; AI551208; CAR; CAR-beta; Care2; ESTM32; MB67
Summary	Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element (By similarity).[UniProtKB/Swiss-Prot Function]

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