Mouse C5ar1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	C5ar1
Locus ID	12273
Kit Components	GA200470G1, C5ar1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200470G2, C5ar1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200470G3, C5ar1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001173550, NM_007577
Synonyms	C5aR; C5r1; Cd88; D7Msu1
Summary	Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.[UniProtKB/Swiss-Prot Function]

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