Mouse C1qc activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	C1qc
Locus ID	12262
Kit Components	GA200462G1, C1qc gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200462G2, C1qc gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200462G3, C1qc gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_007574
Synonyms	AI385742; C1qg; Ciqc
Summary	C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.[UniProtKB/Swiss-Prot Function]

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